 |
Press Articles
 |
| Janie Dubois, Gerald Sando, E. Neil Lewis, Near-Infrared Chemical Imaging, A Valuable Tool for the Pharmaceutical Industry, G.I.T. Laboratory Journal Europe, No. 1-2, 2007 |
|
|
|
| Linda H. Kidder, Janie Dubois, E. Neil Lewis, Realizing the Potential of Near Infrared Chemical Imaging in Pharmaceutical Manufacturing, The Pharmaceutical Solutions Update, Spring (May 9), 48-52, 2007. |
|
|
|
| Janie Dubois, Jean-Claude Wolff, John K. Warrack, Joseph W. Schoppelrei, E. Neil Lewis, NIR Chemical Imaging for Counterfeit Pharmaceutical Products Analysis, Spectroscopy 22(2), 40-50, 2007. |
|
|
|
| Joan Zimmermann, Old Array, New Tricks.
MDA TechUpdate, Fall 2006. |
|
|
|
| Eunah Lee, Wei X. Huang, Patrick Chen, E. Neil Lewis and Richard V. Vivilecchia, High-throughput Analysis of Pharmaceutical Tablet Content Uniformity by Near-Infrared Chemical Imaging.
Spectroscopy 21(11), 24-33, 2006. |
|
|
|
| Linda H. Kidder, Eunah Lee, E. Neil Lewis, NIR Chemical Imaging as a Process Analytical Tool,
Innovations in Pharmaceutical Technology September, 107-111, 2005. |
|
|
|
| E. N. Lewis, L. H. Kidder, E. Lee, NIR Chemical Imaging - Near-Infrared Spectroscopy on Steroids.
NIR News, Vol. 16, No. 6, 2005, 2. |
|
|
|
| E. N. Lewis, E. Lee and L. H. Kidder, Combining Imaging and Spectroscopy: Solving Problems with Near-Infrared Chemical Imaging.
Microscopy Today, Volume 12, No. 6, 11/2004. |
|
|
|
| E. N. Lewis, J. Schoppelrei, E. Lee, Near-infrared Chemical Imaging and the PAT Initiative.
Spectroscopy Magazine, 04/2004, 26-36. |
|
|
|
| E. N. Lewis, J. E. Carroll, F. M. Clarke, A near-infrared view of pharmaceutical formulation analysis.
NIR News, Vol. 12, No. 3, 2001. |
|
|
|
Research Papers and Published Abstracts
2007
|
Janie Dubois, E. Neil Lewis, Frederick S. Fry, Jr., Elizabeth M. Calvey, Near Infrared Chemical Imaging for High Throughput Screening of Food Bacteria. NIR News, Vol. 18, No. 8, 6-8, 2007
|
|
Suzanne J. Hudak, Kenneth S. Haber, Gerald Sando, Linda H. Kidder, E. Neil Lewis, Practical Limits of Spatial Resolution in Diffuse Reflectance NIR Chemical Imaging. NIR News , Vol. 18, No. 6, 4-7, 2007
|
|
E. Neil Lewis, Janie Dubois, Linda H. Kidder and Kenneth Haber, Near-Infrared Chemical Imaging: Beyond the Pictures. In Techniques and Applications of Hyperspectral Image Analysis , Paul Geladi and Hans Grahn (eds), John Wiley and Sons, Chichester, 335-361, 2007.
|
|
2006
|
E. N. Lewis, J. Dubois and L. H. Kidder, NIR Imaging, Instrumentation and its Applications to Agricultural and Food Engineering. In "NIR in Food Science and Technology, Chapter 4.3", Wiley-Interscience, Osaki, McClure (eds.), 2006.
|
|
L. H. Kidder, E. Lee, V. F. Kalasinsky, J.W. Schoppelrei and E. N. Lewis, Forensic Visualization of Foreign Matter in Human Tissue by Near-Infrared Spectral Imaging: Methodology and Data Mining Strategies. Cytometry 69A (8) , Special Issue on Spectral Imaging , J. Lerner, Steve Lockett, Robert Zucher (eds.), 888-896, 2006.
|
|
2005
|
J. Dubois, E. N. Lewis, F. S. Fry, E. M. Clavey, Bacterial identification by near-infrared chemical imaging of food-specific cards.
Food Microbiology 22,, 12/2005, 577-583.
|
|
E. N. Lewis, J. W. Schoppelrei, E. Lee and L.H. Kidder, NIR Chemical Imaging as a Process Analytical Tool. In "Process Analytical Technology, chapter 7", Blackwell Publishing, K. Bakeev (eds.), 2005, 187.
|
|
E. N. Lewis, L.H. Kidder, E. Lee and K. S. Haber, Near-Infrared Spectral Imaging with Focal-Plane Array Detectors. In "Spectrochemical Analysis Using Multichannel Detectors, chapter 2", Blackwell Publishing, I. Levin, R. Bhargava (eds.), 2005, 25.
|
|
2004
|
R. C. Lyon, C. D. Ellison, E. H. Jefferson, E. N. Lewis, E. Lee, L. H. Kidder, A. S. Hussain, Detecting Solid State Forms in Drug Products by Near-Infrared Spectroscopy and Chemical Imaging. In "FDA Science Forum, Washington, DC", 05/2004.
|
|
C. D. Ellison, R. C. Lyon, E. H. Jefferson, E. N. Lewis, E. Lee, L. H. Kidder, J. K. Drennen, III, A. S. Hussain, Quantitative Detection of Low-Level Impurities in Pharmaceutical Tablets: A Comparison of Near-Infrared Spectroscopy and Chemical Imaging. In "FDA Science Forum, Washington, DC", 05/2004.
|
|
R. C. Lyon, C. D. Ellison, E. H. Jefferson, E. N. Lewis, E. Lee, K. Haber, A. S. Hussain, Screening Pharmaceuticals for Authenticity by Near-Infrared Chemical Imaging. In "Annual Meeting of American Pharmaceutical Scientists, Baltimore, MD", 2004.
|
|
R. C. Lyon, C. D. Ellison, E. H. Jefferson, E. N. Lewis, E. Lee, J. K. Drennen III, A. S. Hussain, Monitoring Drug Product Stability by Near-Infrared Chemical Imaging.. In "Annual Meeting of American Pharmaceutical Scientists, Baltimore, MD", 2004.
|
|
2003
|
R. C. Lyon, C. D. Ellison, E. H. Jefferson, E. N. Lewis, E. Lee, L. H. Kidder, J. K. Drennen III, A. S. Hussain, Detecting Polymorphism and Pseudopolymorphism in Drug Products by Near-Infrared Spectroscopy and Chemical Imaging. In "Annual Meeting of American Pharmaceutical Scientists, Salt Lake City, UT", 10/2003.
|
|
C. D. Ellison, R. C. Lyon, E. H. Jefferson, E. N. Lewis, E. Lee, L. H. Kidder, J. K. Drennen III, A. S. Hussain, Quantitative Detection of Low-Level Impurities in Pharmaceutical Tablets: A Comparison of Near-Infrared Spectroscopy and Chemical Imaging. In "Annual Meeting of American Pharmaceutical Scientists, Salt Lake City, UT", 10/2003.
|
|
R. C. Lyon, E. H. Jefferson, A. S. Carlin, E. Lee, K. H. Haber, E. N. Lewis, A. S. Hussain, Assessing the Authenticity of Pharmaceutical Tablets by Near-Infrared Spectral Imaging. In "FDA Science Forum, Washington, DC", 04/2003.
|
|
R. C. Lyon, E. H. Jefferson, A. S. Carlin, R. L. Hunt, E. Lee, E. N. Lewis, J. K. Drennen, III, A. S. Hussain, Tablet-to-Tablet Variation in Hardness and Dissolution Evaluated by Near-Infrared Spectroscopy and Spectral Imaging. In "FDA Science Forum, Washington, DC", 04/2003.
|
|
L. Zhang, G. W. Small, E. N. Lewis, Classification of Fourier Transform Infrared Microscopic Imaging Data of Human Breast Cells by Cluster Analysis and Artificial Neural Networks.
Applied Spectroscopy 57,, 2003, 14-22.
|
|
M. D. Schaeberle, N. J. Everall, J. Carter, J. M. Chalmers, E. N. Lewis , L. H. Kidder, I. W. Levin, Fourier Transform Infrared Spectroscopic Imaging Microscopy of Thermoplastic-Thermoset Polymer Blends: Effect of Cure Temperature on Phase Segregation.
Vibrational Spectroscopy (in press), 2003.
|
|
2002
|
R. C. Lyon, E. H. Jefferson, A. S. Carlin, R. L. Hunt, E. Lee, E. N. Lewis, J. K. Drennen, III, A. S. Hussain, Tablet-to-Tablet Variation in Hardness and Dissolution Evaluated by Near-Infrared Spectroscopy and Spectral Imaging. In "Annual Meeting of American Pharmaceutical Scientists, Toronto, Ontario", 11/2002.
|
|
E. N. Lewis, E. Lee, R. C. Lyon, J. K. Drennen, III, L. H. Kidder, Infrared Chemical Imaging for Real Time Blend Homogeneity QA/QC in Tablets. In "Annual Meeting of American Pharmaceutical Scientists, Toronto, Ontario", 11/2002.
|
|
R. C. Lyon, E. H. Jefferson, A. S. Carlin, E. Lee, K. H. Haber, E. N. Lewis, A. S. Hussain, Assessing the Authenticity of Pharmaceutical Tablets by Near-Infrared Spectral Imaging.. In "Annual Meeting of American Pharmaceutical Scientists, Toronto, Ontario", 11/2002.
|
|
P. Lasch, W. Haensch, E. N. Lewis , L. H. Kidder, D. Naumann, Characterization of colorectal adenocarcinoma sections by spatially resolved FT-IR microspectroscopy.
Applied Spectroscopy 56, 2002, 1.
|
|
K. J. Zuzak, M. D. Schaeberle, E. N. Lewis, I. W. Levin, Visible reflectance hyperspectral imaging: characterization of a noninvasive, in vivo system for determining tissue perfusion.
Analytical Chemistry 74, 2002, 2021.
|
|
F. W. Koehler, E. Lee, L. H. Kidder, E. N. Lewis, Near-infrared Chemical Imaging: The Practical Choice.
Spectroscopy Europe 41, 2002, 3.
|
|
J. M. Chalmers, N. J. Everall, M. D. Schaerberle, I. W. Levin, E. N. Lewis, L. H. Kidder, J. Wilson, R. Crocombe, FT-IR Imaging of Polymers: An Industrial Appraisal.
Vibrational Spectroscopy, 30, 2002, 43.
|
|
R. C. Lyon, D. S. Lester, E. N. Lewis, E. Lee, L. X. Yu, E. H. Jefferson, A. S. Hussain, Near infrared spectral imaging for quality assurance of pharmaceutical products: analysis of tablets to assess powder blend homogeneity.
AAPS PharmSciTech 3 (3), 2002, 17.
|
|
2001
|
Haka, A. S., L. H. Kidder, E. N. Lewis, A Combined Spectroscopic imaging and chemometric approach for automatically partitioning tissue types in human prostate tissue biopsies. In "Biomarkers and Biological Spectral Imaging", Proc. SPIE 4259, G. Bearman, D. Bornhop, R. Levenson (eds.), 2001, 47.
|
|
L. H. Kidder, A. S. Haka, E. N. Lewis, Fourier Transform Infrared Imaging Microsopy. In "The Handbook of Vibrational Spectroscopy", John Wiley, Chichester, UK, J. M. Chalmers, P. R. Griffith (eds.), 2001, Vol. II.
|
|
E. N. Lewis , J. E. Carroll, F. M. Clarke, NIR Imaging: A Near Infrared View of Phamaceutical Formulation Analysis. In "NIR News 12", 2001, 16.
|
|
2000
|
P. Lasch, E. N. Lewis, L. H. Kidder, D. Naumann, Image Reconstruction of FT-IR Microspectrometric Data. In "Spectral Imaging: Instrumentation, Applications, and Analysis", Proc. SPIE 3920, G. Bearman, D. Cabib, R. Levenson (eds.), 2000, 129.
|
|
K. J. Zuzak, M. D. Schaeberle, E. N. Lewis, I. W. Levin, Visible spectroscopic imaging studies of normal and ischemic dermal tissue. In "Biomedical Spectroscopy: Vibrational Spectroscopy and Other Novel Techniques", Proc. SPIE 3918, A. Mahadevan-Jansen, G. Puppels (eds.), 2000, 17.
|
|
Schaeberle, M. D., I. W. Levin, E. N. Lewis, Biological Vibrational Spectroscopic Imaging. In "Infrared and Raman Spectroscopy of Biological Materials", Marcel Dekker, Inc., New York, H-U Gremlich, B. Yan (eds.), 2000, 231-258.
|
|
Salzer, R., Steiner, G., Mantsch, H.H., Mansfield J. and Lewis, E.N., Infrared and Raman Imaging of Biological and Biomimetic Samples.
Fresenius, J. Anal. Chem. 366, 2000, 712-726.
|
|
1999
|
L. H. Kidder, P. Colarusso, S. A. Stewart, I. W. Levin, N. M. Appel, D. S. Lester, P. G. Pentchev, E. N. Lewis, Infrared Spectroscopic Imaging of the Biochemical Modifications Induced in the Cerebellum of the Niemann-Pick type C Mouse. In "Journal of Biomedical Optics 41, 1", 1999, 7-13.
|
|
P. Colarusso, A. Whitley, I. W. Levin, E. N. Lewis, Raman microscopy and imaging of inorganic and biological materials with liquid crystal tunable filters. In "Biomedical Applications of Raman Spectroscopy", Proc. SPIE 3608, M. D. Morris (eds.), 1999, 139.
|
|
Y. Guan, E. N. Lewis, I. W. Levin, Biomedical Applications of Raman Spectroscopy: Tissue Differentiation and Potential Clinical Usage. In "Analytical Applications of Raman Spectroscopy", Blackwell Science, M. Pelletier (eds.), 1999, 276.
|
|
C. Marcott, R. C. Reeder, FT-IR Spectroscopic Imaging Microscopy using an MCT Focal-Plane Array Detector.
American Institute of Physics Proceedings 430, 1999, 377-378.
|
|
1998
|
L. H. Kidder, I. W. Levin, E. N. Lewis, Infrared Spectroscopic Imaging Microscopy: Applications to Biological Systems. In "Fourier Transform Spectroscopy, Eleventh International Conference", American Institute of Physics Conference Proceedings 430, J. A. de Haseth (eds.), 1998, 148.
|
|
L. H. Kidder, A. S. Haka, P. J. Faustino, D. S. Lester, I. W. Levin, E. N. Lewis, Infrared Spectroscopic Imaging as a Tool for Pathology.
Proc. SPIE 3257, 1998.
|
|
P. Colarusso, L. H. Kidder, I. W. Levin, J. C. Fraser, E. N. Lewis, Infrared Spectroscopic Imaging: from Planetary to Cellular Systems.
Applied Spectroscopy 52, 3, 1998, 106A.
|
|
D. S Lester, L. H. Kidder, I. W. Levin, E. N. Lewis, Infrared Microscopic Imaging of the Cerebellum of Normal and Cytarabine Treated Rats.
Cellular and Molecular Biology 44, 1,, 1998, 29.
|
|
C. Marcott, R. C. Reeder, E. P. Paschalis, D. N. Talakis, A. L. Boskey, R. Mendelsohn, Infrared Microspectroscopic Imaging of Biomineralized Tissues using a Mercury-Cadmium-Telluride Focal-Plane Array Detector.
Cellular and Molecular Biology 44, 1998, 109-115.
|
|
S. J. Oh, J. L. Koenig, Phase and Curing Behavior of Polybutadiene/Diallyl Phthalate Blends Monitored by FT-IR Imaging Using Focal Plane Array Detection.
Analytical Chemistry 70, 1998, 1768-1772.
|
|
C. M. Snively, J. L. Koenig, Application of Real Time Mid-Infrared FTIR Imaging to Polymeric Systems, Diffusion of Liquid Crystals into Polymers.
Macromolecules 31, 1998, 3753-3755.
|
|
N. A. Wright, R. A. Crocombe, D. L. Drapcho, W. J. McCarthy, The Design and Performance of a Mid-Infrared FT-IR Spectroscopic Imaging System.
American Institute of Physics Proceedings 430, 1998, 371-372.
|
|
C. L. Bennett, LIFTIRS, The Livermore Imaging FTIR Spectrometer.
American Institute of Physics Proceedings 430, 1998, 170-186.
|
|
R. Bhargava, S. Wang, J. L. Koenig, FR-IR Imaging of the Interface in Multicomponent Systems Using Optical effects Induced by Differences in Refractive Index.
Applied Spectroscopy 52, 1998, 323-328.
|
|
J. M. Chalmers, N. J. Everall, K. Hewitson, M. A. Chesters, M. Pearson, A. Grady, B. Kuzicka, Fourier transform infrared microscopy: some advances in techniques for characterisation and structure-property elucidations of industrial material.
The Analyst 123, 1998, 579-586.
|
|
1997
|
B. Foster, Focus on microscopy-Microchemical imaging: A powerful new bridge between microscopy imaging and chemical analysis.
American Laboratory, 02/1997.
|
|
E. N. Lewis, L. H. Kidder, I. W. Levin, V. F. Kalasinsky, J. P. Hanig, D. S. Lester, Applications of Fourier Transform Infrared Imaging Microscopy in Neurotoxicity. In "Emerging Technologies in Brain Sciences", Annals of the New York Academy of Sciences, , Lester, D.S., Felder, C.C., E. N. Lewis (eds.), 1997, Vol. 820.
|
|
L. H. Kidder, V. F. Kalasinsky, J. L. Luke, I. W. Levin, E. N. Lewis, Visualization of Silicone Gel in Human Breast Tissue Using a New Infrared Imaging Spectrsocopy.
Nature Medicine 3, 2, 1997, 235.
|
|
E. N. Lewis , L. H. Kidder, J. F. Arens, M. C. Peck, I. W. Levin, Si:As Focal-Plane Array Detection for Fourier Transform Spectroscopic Imaging in the Infrared Fingerprint Region.
Applied Spectroscopy 51, 4, 1997, 563.
|
|
L. H. Kidder, I. W. Levin, E. N. Lewis , V. F. Kleiman, E. J. Heilweil, MCT Focal-Plane Array Detection for Mid-Infrared Fourier Transform Spectroscopic Imaging.
Optics Letters, 22, 10, 1997, 742.
|
|
E. N. Lewis, I. W. Levin, R. A. Crocombe, Applications of Infrared Imaging with a Focal Plane Array Detector and a Step-Scan FT-IR Spectrometer.
Mikrochimica Acta [Suppl.] 14, 1997, 589-590.
|
|
L. H. Kidder, V. F. Kalasinsky, J. L. Luke, I. W. Levin, E. N. Lewis, Visualization of silicone gel in human breast tissue using new infrared imaging spectroscopy.
Nature Medicine 3 (2), 1997, 235-237.
|
|
L. H. Kidder, I. W. Levin, E. N. Lewis, V. D. Kleiman, E. J. Heilweil, MCT focal-plane array detection for mid-infrared FT spectroscopic imaging.
Optical Letter 22, 1997, 742.
|
|
R. A. Crocombe, N. Wright, D. L. Drapcho, W. J. McCarthy, P. Bhandare, E. Y. Jiang, FT-IR spectroscopic imaging in the infrared 'fingerprint' region using an MCT array detector.
Microscopy and Micranalysis Vol. 3, Supplement 2, Springer-Verlag, Inc., New York, 1997, 863-864.
|
|
1996
|
X. Wang, E. N. Lewis, Acousto-Optic Tunable Filters (AOTFs) and their Application in Spectroscopic Imaging and Microscopy. In "Fluorescence Imaging Spectroscopy and Microscopy", Wiley-Interscience, 1996.
|
|
E. N. Lewis, A. M. Gorbach, C. Marcott, I. W. Levin, Fourier Transform Near-Infrared Spectroscopic Imaging Microscopy of Mammalian Brain Slices.
Applied Spectroscopy 50, 1996, 263.
|
|
S. Goldstein L. H. Kidder, T. Herne, I. W. Levin, E. N. Lewis, The Development of High Resolution AOTF Raman Imaging Microscopy for Biological Applications.
Journal of Microscopy 184, 1996, 35.
|
|
M. D. Schaerberle, V. F. Kalasinsky, J. L. Luke, E. N. Lewis, I. W. Levin, P. J. Treado, Raman Chemical Imaging: Histopathology of Inclusions in Human Breast Tissue.
Analytical Chemistry 68, 1996, 1829.
|
|
1995
|
E. N. Lewis, I. W. Levin, Vibrational Spectroscopic Microscopy, Raman, Near-Infrared and Mid-Infrared Imaging Techniques.
Journal of the Microscopy Society of America 1, 1995, 1.
|
|
E. N. Lewis, I. W. Levin, Real-Time, Mid-Infrared Spectroscopic Imaging Microscopy Using Indium Antimonide Focal-Plane Array Detection.
Applied Spectroscopy 49, 1995, 672.
|
|
E. N. Lewis, P. J. Treado, Reeder, R.C., Story, G.M., Dowrey, A.E., Marcott, C., I. W. Levin, Fourier Transform Step-Scan Imaging Interferometery: High-Definition Chemical Imaging in the Infrared Spectral Region.
Analytical Chemistry 67, 1995, 3377.
|
|
E. N. Lewis, A. M. Gorbach, C. Marcott, I. W. Levin, High-Fidelity FTIR spectroscopic imaging of primate brain tissue.
Applied Spectroscopy 50, 1995, 263.
|
|
E. N. Lewis, P. J. Treado, R. C. Reeder, G. M. Story, A. E. Dowrey, C. Marcott, I. W. Levin, FTIR spectroscopic imaging using an infrared focal-plane array detector.
Analytical Chemistry 67, 1995, 3377.
|
|
1994
|
E. N. Lewis, P. J. Treado, I. W. Levin, Near-Infrared and Raman Spectroscopic Imaging.
American Laboratory, 06/1994, 16.
|
|
I. W. Levin, E. N. Lewis, Applications of Fourier-Transform Raman Spectroscopy to Biological Assemblies. In "in "Fourier-Transform Raman Spectroscopy"", Academic Press, 1994, 1.
|
|
P. J. Treado I. W. Levin, E. N. Lewis, Near-Infrared Spectroscopic Imaging Microscopy of Biological Materials Using an Infrared Focal-Plane Array and an Acousto-Optic Tunable Filter (AOTF).
Applied Spectroscopy 48, 1994, 5.
|
|
1993
|
E. N. Lewis, P. J. Treado, I. W. Levin, A Miniaturized, No-Moving-Parts Raman Spectrometer.
Applied Spectroscopy 47, 1993, 539.
|
|
1992
|
P. J. Treado, I. W. Levin, E. N. Lewis, Near-Infrared Acousto-Optic Spectroscopic Microscopy: A Solid-State Approach to Chemical Imaging.
Applied Spectroscopy 46, 1992, 553.
|
|
P. J. Treado, I. W. Levin, E. N. Lewis, High Fidelity Raman Imaging Spectrometry: A Rapid Method Using an Acousto-Optic Tunable Filter.
Applied Spectroscopy 46, 1992, 1211.
|
|
E. N. Lewis, P. J. Treado, I. W. Levin, Raman Imaging Microscopy: A Solid-State Approach Using an Acousto-Optic Tunable Filter (AOTF).
Proceedings of the Thirteenth International Conference on Raman Spectroscopy, 1992, 1072.
|
|
Patents
|
E. N. Lewis, I. W. Levin, P. J. Treado, Spectroscopic Imaging Device using Imaging Quality Spectral Filters,
U.S. Patent 5,377,003, 12/27/1994.
|
|
E. N. Lewis, I. W. Levin, P. J. Treado, Spectroscopic Imaging Device using Imaging Quality Spectral Filters,
U.S. Patent 5,528,368, 06/18/1996.
|
|
E. N. Lewis, D. J. Strachan, L. H. Kidder, High-volume on-line spectroscopic composition testing of manufactured pharmaceutical dosage units,
U.S. Patent 6,690,464, 02/18/2000.
|
|
E. N. Lewis, High-Throughput Infrared Spectroscopy,
U.S. Patent 6,483,112, 11/01/2002.
|
|
|
|
Home
